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human brain tissue  (Human Protein Atlas)

 
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    Human Protein Atlas human brain tissue
    Human Brain Tissue, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+brain+tissue/brain+human+tissue/pm42031726-324-8-23
    Average 86 stars, based on 1 article reviews
    human brain tissue - by Bioz Stars, 2026-09
    86/100 stars

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    Related Articles

    Gene Expression:

    Article Title: Phagocytosing differentiated cell-fragments is a novel mechanism for controlling somatic stem cell differentiation within a short time frame.
    Article Snippet: .. The gene expression of Tissue and Cell Type in the human brain, liver, and muscle tissue (heart and skeletal muscle) was acquired from The Human Protein Atlas (http:// www. prote inatl as. org) [33]. .. For pseudotemporal depiction of the heatmap, The Human Protein Atlas [33], and BigGPS (http:// biogps. org/# goto= welco me) [45] were referred to for selecting lineage-specific markers.

    Staining:

    Article Title: βIII-tubulin can act as a brake on extrinsic apoptosis in pancreatic cancer.
    Article Snippet: .. We also showed positive staining of βIII-tubulin in human brain tissue, and negative staining in normal pancreas tissue, consistent with expression in the human protein atlas (Supplementary Figure 21). ..

    Negative Staining:

    Article Title: βIII-tubulin can act as a brake on extrinsic apoptosis in pancreatic cancer.
    Article Snippet: .. We also showed positive staining of βIII-tubulin in human brain tissue, and negative staining in normal pancreas tissue, consistent with expression in the human protein atlas (Supplementary Figure 21). ..

    Expressing:

    Article Title: βIII-tubulin can act as a brake on extrinsic apoptosis in pancreatic cancer.
    Article Snippet: .. We also showed positive staining of βIII-tubulin in human brain tissue, and negative staining in normal pancreas tissue, consistent with expression in the human protein atlas (Supplementary Figure 21). ..

    Genome Wide:

    Article Title: The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia–reperfusion brain injury in mice
    Article Snippet: .. According to genome-wide analysis of human brain tissue in Human Protein Atlas (http://www.proteinatlas.org) [37], the highest CHRNA7 RNA expression levels are found in cortex, hypothalamus, pons and medulla, with similar patterns in mouse brain based on RNA-seq data (https://www.proteinatlas.org/ENSG00000175344-CHRNA7/brain). ..

    RNA Expression:

    Article Title: The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia–reperfusion brain injury in mice
    Article Snippet: .. According to genome-wide analysis of human brain tissue in Human Protein Atlas (http://www.proteinatlas.org) [37], the highest CHRNA7 RNA expression levels are found in cortex, hypothalamus, pons and medulla, with similar patterns in mouse brain based on RNA-seq data (https://www.proteinatlas.org/ENSG00000175344-CHRNA7/brain). ..

    RNA Sequencing:

    Article Title: The selective alpha7 nicotinic acetylcholine receptor agonist AR-R17779 does not affect ischemia–reperfusion brain injury in mice
    Article Snippet: .. According to genome-wide analysis of human brain tissue in Human Protein Atlas (http://www.proteinatlas.org) [37], the highest CHRNA7 RNA expression levels are found in cortex, hypothalamus, pons and medulla, with similar patterns in mouse brain based on RNA-seq data (https://www.proteinatlas.org/ENSG00000175344-CHRNA7/brain). ..



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    Image Search Results


    PVSRIPO directs infection of, non-cytopathogenic vRNA replication in, and IFN-I signaling in the microglial compartment in vivo . (A-C) Flow cytometry analyses of microglia before/after CD11b + -bead isolation from hCD155 -tg mouse (A, C) or human brain tissue (B) . The same kit and identical procedures were used to process human/mouse brain tissue samples (see Materials and methods ). Consistently, ∼90-95% of CD45 hi , CD11b + , MERTK + , Cx3cx1 + (A, B) and Tmem119 + (C) cells were recovered from brain tissue of either species. (D) RT-qPCR analyses of total RNA from hCD155 -tg murine or human microglia as shown. Microglia were either infected ex vivo [multiplicity of infection (MOI) 10; left and middle panels], or CD11b + -bead isolated after infection in vivo [single intracerebral inoculation of PVSRIPO (5 x 10 7 pfu); right panel]. Ipsilateral (to the site of virus inoculation) and contralateral hemispheres were processed separately. vRNA levels in mouse microglia were analyzed by two-tailed Mann-Whitney test on ΔΔCt values at 8 weeks pi (n=5; left panel); the same test was used to analyze vRNA levels in human microglia at 72hpi (n=3; right middle panel). (E) HCR-FISH analyses of vRNA species in human CD11b + -bead isolated microglia infected ex vivo with PVSRIPO (MOI 10). Two individual microglia cells at 24 and 72hpi, each, are shown. (F-G) IF and HCR-FISH analyses in non-tumor-bearing hCD155 -tg mouse brains 48h post single intracerebral PVSRIPO infusion (5 x 10 7 pfu). Tmem119 + microglia stain positive for (-)strand vRNA (F) with widespread ISG15 induction in the microglial compartment (G) .

    Journal: bioRxiv

    Article Title: Viral Microglia Reprogramming Clears Oligomeric Neurotoxic Debris

    doi: 10.64898/2026.04.06.716590

    Figure Lengend Snippet: PVSRIPO directs infection of, non-cytopathogenic vRNA replication in, and IFN-I signaling in the microglial compartment in vivo . (A-C) Flow cytometry analyses of microglia before/after CD11b + -bead isolation from hCD155 -tg mouse (A, C) or human brain tissue (B) . The same kit and identical procedures were used to process human/mouse brain tissue samples (see Materials and methods ). Consistently, ∼90-95% of CD45 hi , CD11b + , MERTK + , Cx3cx1 + (A, B) and Tmem119 + (C) cells were recovered from brain tissue of either species. (D) RT-qPCR analyses of total RNA from hCD155 -tg murine or human microglia as shown. Microglia were either infected ex vivo [multiplicity of infection (MOI) 10; left and middle panels], or CD11b + -bead isolated after infection in vivo [single intracerebral inoculation of PVSRIPO (5 x 10 7 pfu); right panel]. Ipsilateral (to the site of virus inoculation) and contralateral hemispheres were processed separately. vRNA levels in mouse microglia were analyzed by two-tailed Mann-Whitney test on ΔΔCt values at 8 weeks pi (n=5; left panel); the same test was used to analyze vRNA levels in human microglia at 72hpi (n=3; right middle panel). (E) HCR-FISH analyses of vRNA species in human CD11b + -bead isolated microglia infected ex vivo with PVSRIPO (MOI 10). Two individual microglia cells at 24 and 72hpi, each, are shown. (F-G) IF and HCR-FISH analyses in non-tumor-bearing hCD155 -tg mouse brains 48h post single intracerebral PVSRIPO infusion (5 x 10 7 pfu). Tmem119 + microglia stain positive for (-)strand vRNA (F) with widespread ISG15 induction in the microglial compartment (G) .

    Article Snippet: Microglia were isolated from freshly dissected mouse brains or from epilepsy surgery human brain tissues using a CD11b + -bead isolation kit (Miltenyi MicroBeads, human & mouse; #130-097-142) as described in detail previously ( ).

    Techniques: Infection, In Vivo, Flow Cytometry, Isolation, Quantitative RT-PCR, Ex Vivo, Virus, Two Tailed Test, MANN-WHITNEY, Staining